Camilla Jessen
Japanese researchers are exploring a surprising method of delivering oxygen to the body.
Researchers in Japan have completed the first human trial of a groundbreaking method that may allow people to absorb oxygen through their intestines.
This process is known as enteral ventilation.
The early-stage trial, led by Professor Takanori Takebe of Osaka University and Cincinnati Children’s Hospital, tested the safety of introducing a synthetic, oxygen-carrying fluid through the rectum.
The results showed the procedure was tolerated well by healthy participants, with no serious side effects, only mild discomfort and bloating.
“This isn’t a replacement for breathing,” the research team said, “but it may provide a critical backup when the lungs cannot function.”
What is enteral ventilation?
The method involves introducing a fluid known as perfluorocarbon into the lower intestine, where it can deliver oxygen to the blood through the gut’s dense network of capillaries.
The fluid is already used in some experimental medical treatments due to its ability to carry large amounts of oxygen.
Previous tests in mice and pigs showed that this unconventional pathway could work in animals. The new human trial marks the first step in determining whether it could be used in emergency care.
Next step: testing oxygen delivery
In this trial, researchers used a non-oxygenated version of the fluid to test for tolerance.
The next phase will involve using oxygenated fluid to see whether it can meaningfully raise blood oxygen levels — and how much is needed.
Potential use in emergencies
Scientists say the method could help in critical situations such as lung collapse, smoke inhalation, allergic reactions, or treatment of premature infants with underdeveloped lungs.
“This is about buying time when every second counts,” Takebe said.
The study is still in early stages, but researchers say the concept opens new paths for non-lung-based oxygen support, especially in extreme medical emergencies.
The article is based on information from MedicalXpress.
This article is made and published by Camilla Jessen, who may have used AI in the preparation
