Homepage Science “He differs very significantly from the general population”: Scientists tested...

“He differs very significantly from the general population”: Scientists tested Hitler’s DNA and uncovered a rare condition

Adolf Hitler
Bundesarchiv, Bild 146-1990-048-29A / CC-BY-SA 3.0, CC BY-SA 3.0 DE , via Wikimedia Commons

Wars have a habit of leaving weird souvenirs behind. Most end up gathering dust on closet shelves or in forgotten museum drawers. But ever so often, one of those odd relics ends up under a microscope and changes what people thought they knew.

When Adolf Hitler ended his life in his Berlin bunker in April 1945, his blood soaked into the sofa fabric. An American soldier later sliced away a scrap of that bloodstained upholstery, which ended up preserved inside an American museum. Decades later, modern tools finally made it possible to extract and study that ancient sample.

Professor Turi King from the University of Bath led the investigation, matching the sample against a known living relative of Hitler. That test confirmed the blood was almost certainly his. From there, King and her team mapped the dictator’s genetic code to uncover several unexpected medical markers.

They also addressed an old historical rumor, writes science site Forskning. The analysis turned up no evidence to support the long-standing claim that Hitler had Jewish ancestry.

Rare hormone disorder

Beyond that debunked myth, the genetic map showed a mutation in the PROK2 gene. That specific variation points toward Kallmann syndrome, a rare condition that disrupts hormone production and drops testosterone levels.

The condition often delays puberty and can impair genital development. In some men, it leads to an undescended testicle, a condition noted in a 1923 medical record from Hitler’s time in prison.

Still, experts stress that the record alone does not prove the diagnosis, nor does it confirm historical speculation about a micropenis. Instead, the biological marker offers fresh context for historians who study his difficult relationships with women.

High psychiatric scores

Researchers in Denmark then tested his DNA against a modern population database. Professor Ditte Demontis from Aarhus University compared Hitler’s profile with genetic data from 37,000 Danish individuals to calculate polygenic risk scores.

Hitler scored within the top one percent for autism, schizophrenia, and bipolar disorder. Not a single person in the 37,000 comparison group scored that high across all three conditions at once.

Even so, Demontis stressed caution. In modern populations, people with those high genetic scores have only a five percent chance of developing those illnesses. Genetic risk never excuses or explains his atrocities.

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